Cytosolic translocation
WebAug 1, 2024 · There was a significant (P < 0.001) and concomitant depletion of the cell membrane and cytosolic signal of Cx43 in Wnt-treated cells with an increase in the … WebDec 30, 2024 · Depending on their relative locations, they may be considered either start -transfer or stop -transfer sequence, where “transfer” refers to translocation of the peptide through the translocon. This is easiest to understand by referring to Figure 11.2. 5. Figure 11.2. 5. Single-pass transmembrane protein insertion.
Cytosolic translocation
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WebMar 14, 2024 · Bagaev, A.V., Garaeva, A.Y., Lebedeva, E.S. et al. Elevated pre-activation basal level of nuclear NF-κB in native macrophages accelerates LPS-induced translocation of cytosolic NF-κB into the ... WebDec 18, 2013 · Here, PINK1 is shown to participate in maintaining a healthy pool of mitochondria also by functioning in the cytosol, where it interacts with Parkin. Cleaved PINK152 is retrotranslocated from mitochondria …
WebDec 20, 2024 · Fused in sarcoma/translated in liposarcoma (FUS) is an RNA-binding protein, and its mutations are associated with neurodegenerative diseases, including … WebWe demonstrate here the indispensable role of cytosolic HSP90α in Ag translocation into the cytosol during cross-presentation. Results Cross-Presentation Ability Is Down-Regulated in Bone Marrow-Derived …
WebMar 3, 2012 · Translocation of Parkin to damaged mitochondria induces mitophagy in many non-neuronal cell types [9–16]. However, evidence showing Parkin translocation in primary neurons is controversial [ 9 , 15 , 17 , 18 ], leaving unanswered questions as to how and where Parkin-mediated mitophagy occurs in neurons. WebDec 9, 2024 · Here, we demonstrate that late endosomes, a type of prelysosomal organelles, facilitate actin-cytoskeleton remodeling via cytosolic translocation of …
WebMay 1, 2004 · Increased cytosolic Ca2+ and calcineurin activation stimulated Bad translocation since BAPTA [bis-(o-aminophenoxy)ethane-N, N, N', N'-tetra-acetic acid], an intracellular Ca2+ chelator, and cyclosporin A, a calcineurin inhibitor, significantly reduced translocation. BAPTA also blocked release of cytochrome c from mitochondria as well …
WebJan 17, 2013 · However, the exact mechanism by which CaM mediates sorting and translocation of the small secretory proteins into the ER is largely unknown. Protein import into chloroplasts and mitochondria occurs posttranslationally. Similar to ER targeting, cytosolic factors are likely to be involved in the protein import into these endosymbiotic … diatoms and cyanobacteriaWebMar 16, 2016 · Cytosolic translocation of Mtb is facilitated through PLA 2 activation. ( A ) THP-1 cells were infected with the Mtb strains either in the absence (−) or presence (+) … diatoms are a type of protozoanWebApr 15, 2010 · Thus, intravacuolar Salmonella senses host cytosolic pH, resulting in the degradation of regulatory complex proteins and effector translocation. Type III secretion … diatoms are they autotrophs or heterotrophsWebDec 20, 2024 · Fused in sarcoma/translated in liposarcoma (FUS) is an RNA-binding protein, and its mutations are associated with neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), through the DNA damage stress response, aberrant stress granule (SG) formation, etc. We previously reported that translocation of … diatoms are mostlyWebOur results show that IP3 generation yields cytosolic Ca2+ rise and NFATc3 translocation. Moreover, near-UV light exposure generates reactive oxygen species (ROS), resulting in … diatoms are good indicator of water pollutionWebApr 26, 2024 · An effect of long PEG linkers on cytosolic arrival was previously reported for the cell-penetrating peptide TAT-PEG-GWWG: PEG 12 or PEG 18 diminished the … citing formatWebApr 24, 2024 · Mycobacterial cytosolic translocation was measured by CCF-4 FRET assay as previously described (17, 22, 50). Briefly, RAW264.7 cells were plated in triplicate in a … diatoms are a type of algae